Valproic acid induced hyperammonaemic encephalopathy: case report

Gül Eryılmaz; Işıl Göğcegöz Gül; Barış Önen Ünsalver; Celal Salçini; Esra Sağlam

doi:10.5455/jmood.20140414121325

2024, Vol: 14, Issue: 1

14 / 1Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

COPYRIGHT FORM
_Title_Page_Obligatory_(v2r)_

Case Report

Online Publishing Date:
30 / 12 / 2014

PBS. 2014; 4(4): 182-5

doi: 10.5455/jmood.20140414121325

Valproic acid induced hyperammonaemic encephalopathy: case report

Gül Eryılmaz, Işıl Göğcegöz Gül, Barış Önen Ünsalver, Celal Salçini, Esra Sağlam.

Abstract
Hyperammonemia is a well-known adverse effect of valproic acid therapy. In the recent years, encephalopathy cases triggered by vaproic acid use-related hyperammonemia have been reported and regular blood ammonium level follow-up is suggested. Polypharmacy, malnutrition, urea cycle disorders are risk factors for encephalopathy triggered by vaproic acid related hyperammonemia. Here, we report a case of symptomatic non-hepatic encephalopathy during valproic acid treatment combined with electroconvulsive therapy (ECT). Valproic acid may have induced hyperammonemic encephalopathy in combination with the anesthetic agent propofol. We may suggest that patients receiving combination of valproic acid and propofol as induction agents for ECT, clinicians should be careful for the development of hyperammonaemic encephalopathy.

Key words: valproic Acid, non-hepatic encephalopathy, Propofol, electroconvulsive therapy

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Gül Eryılmaz Articles by Işıl Göğcegöz Gül Articles by Barış Önen Ünsalver Articles by Celal Salçini Articles by Esra Sağlam
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam. [Valproic acid induced hyperammonaemic encephalopathy: case report]. PBS. 2014; 4(4): 182-5. Turkish. doi:10.5455/jmood.20140414121325

Web Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam. [Valproic acid induced hyperammonaemic encephalopathy: case report]. https://www.pbsciences.org/?mno=149983 [Access: April 11, 2024]. Turkish. doi:10.5455/jmood.20140414121325

AMA (American Medical Association) Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam. [Valproic acid induced hyperammonaemic encephalopathy: case report]. PBS. 2014; 4(4): 182-5. Turkish. doi:10.5455/jmood.20140414121325

Vancouver/ICMJE Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam. [Valproic acid induced hyperammonaemic encephalopathy: case report]. PBS. (2014), [cited April 11, 2024]; 4(4): 182-5. Turkish. doi:10.5455/jmood.20140414121325

Harvard Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam (2014) [Valproic acid induced hyperammonaemic encephalopathy: case report]. PBS, 4 (4), 182-5. Turkish. doi:10.5455/jmood.20140414121325

Turabian Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam. 2014. [Valproic acid induced hyperammonaemic encephalopathy: case report]. Psychiatry and Behavioral Sciences, 4 (4), 182-5. Turkish. doi:10.5455/jmood.20140414121325

Chicago Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam. "[Valproic acid induced hyperammonaemic encephalopathy: case report]." Psychiatry and Behavioral Sciences 4 (2014), 182-5. Turkish. doi:10.5455/jmood.20140414121325

MLA (The Modern Language Association) Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam. "[Valproic acid induced hyperammonaemic encephalopathy: case report]." Psychiatry and Behavioral Sciences 4.4 (2014), 182-5. Print.Turkish. doi:10.5455/jmood.20140414121325

APA (American Psychological Association) Style

Gul Eryılmaz, Işıl Goğcegoz Gul, Barış Onen Unsalver, Celal Salcini, Esra Sağlam (2014) [Valproic acid induced hyperammonaemic encephalopathy: case report]. Psychiatry and Behavioral Sciences, 4 (4), 182-5. Turkish. doi:10.5455/jmood.20140414121325

Author Login Reviewer Login

About Psychiatry and Behavioral Sciences

Contact Information

How to cite this article