Article Type: Case Reports
Spontaneous Erection and Ejaculation Caused by Escitalopram
Betul Kurtses Gursoy
Sexual dysfunction (SD) caused by antidepressants is a common problem encountered in psychiatry outpatient clinics. Documented frequency of this side effect varies in accordance with physician’s inquiry. While questioning about sexual side effects, physicians mostly consider the loss of sexual desire and delay in erection and ejaculation. However, the fact that some selective serotonin reuptake inhibitors (SSRIs) can cause spontaneous erection or spontaneous ejaculation without erection, should not be neglected. This study presents a case of 40-year-old male patient with spontaneous erection and spontaneous ejaculation after escitalopram therapy. It was observed that when treatment with escitalopram was discontinued and citalopram was initiated, these current sexual side effects have changed and loss of sexual desire and delay in ejaculation has begun. The present case is regarding the different sexual side effects caused by similar drugs in the same patient.

Key words: Adverse effects, citalopram, escitalopram, ejaculation, penile erection
Psychiatry and Behavioral Sciences 2018;8(1):38-40
REFERENCES
1.Montejo-Gonzalez AL, Liorca G, Izquierdo JA, Ledesma A, Bouso-o M, Calcedo A, et al. SSRI-induced sexual dysfunction: Fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients. J Sex Marital Ther 1997;23(3):176-94.

2.Stahl SM. The psychopharmacology of sex, part 2: Effects of drugs and disease on the 3 phases of human sexual response. J Clin Psychiatry 2001;62(3):147-8.

3.La Torre A, Giupponi G, Duffy D, Conca A, Catanzariti D. Sexual Dysfunction Related to Drugs: A Critical Review. Part IV: Cardiovascular Drugs. Pharmacopsychiatry 2014;48(1):1-6.

4.Chiesa A, Serretti A. Antidepressivi e disfunzione sessuale: Epidemiologia, meccanismi e strategie di trattamento. Ital J Psychopathol 2010;16(1):104-13.

5.Montgomery SA, Baldwin DS, Riley A. Antidepressant medications: A review of the evidence for drug-induced sexual dysfunction. J Affect Disord 2002;69(1-3):119-40.

6.Williams VSL, Edin HM, Hogue SL, Fehnel SE, Baldwin DS. Prevalence and impact of antidepressant-associated sexual dysfunction in three European countries: Replication in a cross-sectional patient survey. J Psychopharmacol 2010;24(4):489-96.

7.Reisman Y. Sexual Consequences of Post-SSRI Syndrome. Sex Med Rev 2017;5(4):429-33.

8.Kose S, Akin E, Cetin M. Adverse drug reactions and causality: the Turkish version of Naranjo Adverse Drug Reactions Probability Scale. Psychiatry and Clinical Psychopharmacology 2017; 27: 205-6.

9.Morris PL. Fluoxetine and orgasmic sexual experiences. Int J Psychiatry Med 1991;21(4):379-82.

10.Garcia-Campayo J, Sanz-Carrillo C, Lobo A. Orgasmic sexual experiences as a side effect of fluoxetine: a case report. Acta Psychiatr Scand 1995;91(1):69-70.

11.Modell J. Repeated observations of yawning, clitoral engorgement, and orgasm associated with fluoxetine administration. J Clin Psychopharmacol 1989;9:63-5.

12.Pae CU, Kim TS, Lee KU, Kim JJ, Lee CU, Lee SJ, et al. Paroxetine-associated spontaneous sexual stimulation. Int Clin Psychopharmacol 2005;20(6):339-41.

13.Greil W, Horvath A, Sassim N, Erazo N, Grohmann R. Disinhibition of libido: An adverse effect of SSRI? J Affect Disord 2001;62(3):225-8.

14.Virit O, Savas HA. Citalopram-associated spontaneous ejaculations. J Clin Psychopharmacol 2008;28(3):360-1.

15.Belli H, Aslaner D, Ural C, Vardar MK, Yesilyurt S, Gul ES. Escıtalopram Related Erectıle Dysfunctıon and Spontaneous Ejaculatıon durıng. West Indian Med J 2010;59(4):715-6.

16.Ashton AK, Mahmood A, Iqbal F. Improvements in SSRI/SNRI-induced sexual dysfunction by switching to escitalopram. J Sex Marital Ther 2005;31(3):257-62.

17.Keks NA, Hope J, Culhane C. Management of antidepressant induced sexual dysfunction. Australas Psychiatry 2015;22(6):525-8.

18.Baldwin DS, Foong T. Antidepressant drugs and sexual dysfunction. Br J Psychiatry 2013;202(6):396-7.
Online ISSN: 2636-834X
Creative Commons License This work is licensed under a Creative Commons Attribution 3.0 Unported License