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Case Report 


Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh.

Abstract
We report the case of a 20 year old unmarried female patient who has been diagnosed as schizophrenia with intellectual disability. Patient was on chlorpromazine since last three years subsequently develop hyperprolactinemia, later manifested into fibrocystic breast disease. Hyperprolactinemia, is known for decades as neglected side effect of antipsychotic medication. Prolactin is secreted in a pulsatile manner by the anterior pituitary gland. The main physiological function of prolactin is to cause breast enlargement and galactorrhea initially and later develop to fibrocystic breast disease. Routine investigation also revealed hypothyroidism. Prolactin is known as immunomodulator, and has been linked to benign or malignant tumor growth.

Key words: hyperprolactinemia, hypothyroidism, chlorpromazine, fibrocystic breast disease


 
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How to Cite this Article
Pubmed Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS. 2016; 6(4): 230-3. doi:10.5455/jmood.20161122123332


Web Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. https://www.pbsciences.org/?mno=240690 [Access: December 15, 2023]. doi:10.5455/jmood.20161122123332


AMA (American Medical Association) Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS. 2016; 6(4): 230-3. doi:10.5455/jmood.20161122123332



Vancouver/ICMJE Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS. (2016), [cited December 15, 2023]; 6(4): 230-3. doi:10.5455/jmood.20161122123332



Harvard Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh (2016) Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS, 6 (4), 230-3. doi:10.5455/jmood.20161122123332



Turabian Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh. 2016. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. Psychiatry and Behavioral Sciences, 6 (4), 230-3. doi:10.5455/jmood.20161122123332



Chicago Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh. "Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease." Psychiatry and Behavioral Sciences 6 (2016), 230-3. doi:10.5455/jmood.20161122123332



MLA (The Modern Language Association) Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh. "Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease." Psychiatry and Behavioral Sciences 6.4 (2016), 230-3. Print. doi:10.5455/jmood.20161122123332



APA (American Psychological Association) Style

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh (2016) Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. Psychiatry and Behavioral Sciences, 6 (4), 230-3. doi:10.5455/jmood.20161122123332