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Case Report
Online Published: 30 Sep 2012
 


Manic switch after adjuvant lamotrigine treatment

Meliha Zengin Eroğlu, Gonca Karakuş, Lut Tamam.


Abstract
The neurobiology of switching phenomenon is unclear and no common definition exists to describe it. Several factors such as neurobiological problems, sleep deprivation, and drugs appear to be associated with mood switches. Frequently accused drugs are exogenous corticosteroids, dopaminergic agonists, and antidepressants. Lamotrigine is a mood stabilizer that is used in the treatment of treatment-resistant unipolar depression and bipolar depression. In many clinical trials, manic or hypomanic switch risk of lamotrigine has been reported to be not more than placebo. Here, we report a female patient with recurrent depressive disorder who developed manic switch after adding lamotrigine to her treatment regimen.

Key words: manic switch, lamotrigine, adjunctive therapy


 
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How to Cite this Article
Pubmed Style

Eroğlu MZ, Karakuş G, Tamam L. [Manic switch after adjuvant lamotrigine treatment]. PBS. 2012; 2(3): 129-132. Turkish. doi:10.5455/jmood.20120711044809

Web Style

Eroğlu MZ, Karakuş G, Tamam L. [Manic switch after adjuvant lamotrigine treatment]. https://www.pbsciences.org/?mno=18568 [Access: June 22, 2026]. Turkish. doi:10.5455/jmood.20120711044809

AMA (American Medical Association) Style

Eroğlu MZ, Karakuş G, Tamam L. [Manic switch after adjuvant lamotrigine treatment]. PBS. 2012; 2(3): 129-132. Turkish. doi:10.5455/jmood.20120711044809


Vancouver/ICMJE Style

Eroğlu MZ, Karakuş G, Tamam L. [Manic switch after adjuvant lamotrigine treatment]. PBS. (2012), [cited June 22, 2026]; 2(3): 129-132. Turkish. doi:10.5455/jmood.20120711044809


Harvard Style

Eroğlu, M. Z., Karakuş, . G. & Tamam, . L. (2012) [Manic switch after adjuvant lamotrigine treatment]. PBS, 2 (3), 129-132. Turkish. doi:10.5455/jmood.20120711044809


Turabian Style

Eroğlu, Meliha Zengin, Gonca Karakuş, and Lut Tamam. 2012. [Manic switch after adjuvant lamotrigine treatment]. Psychiatry and Behavioral Sciences, 2 (3), 129-132. Turkish. doi:10.5455/jmood.20120711044809


Chicago Style

Eroğlu, Meliha Zengin, Gonca Karakuş, and Lut Tamam. "[Manic switch after adjuvant lamotrigine treatment]." Psychiatry and Behavioral Sciences 2 (2012), 129-132. Turkish. doi:10.5455/jmood.20120711044809


MLA (The Modern Language Association) Style

Eroğlu, Meliha Zengin, Gonca Karakuş, and Lut Tamam. "[Manic switch after adjuvant lamotrigine treatment]." Psychiatry and Behavioral Sciences 2.3 (2012), 129-132. Print.Turkish. doi:10.5455/jmood.20120711044809


APA (American Psychological Association) Style

Eroğlu, M. Z., Karakuş, . G. & Tamam, . L. (2012) [Manic switch after adjuvant lamotrigine treatment]. Psychiatry and Behavioral Sciences, 2 (3), 129-132. Turkish. doi:10.5455/jmood.20120711044809


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