Serum resistin levels and metabolic changes in bipolar disorder

Mehmet Yumru; Hasan Serdar Gergerlioğlu; Haluk Asuman Savaş; Kemal Başaralı; Aysun Kalenderoğlu; Sadık Büyükbaş

doi:10.5455/jmood.20120516040842

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Online Published: 29 Jun 2012

PBS. 2012; 2(2): 47-50

doi: 10.5455/jmood.20120516040842

Serum resistin levels and metabolic changes in bipolar disorder

Mehmet Yumru, Hasan Serdar Gergerlioğlu, Haluk Asuman Savaş, Kemal Başaralı, Aysun Kalenderoğlu, Sadık Büyükbaş.

Abstract
Serum Resistin Levels and Metabolic Disturbances in Bipolar Disorder
Aim: Metabolic disturbances in bipolar disorder appears to be a cluster of diseases that demonstrate insulin resistance as their common etiologic factor. The role of several recently discovered adipokines such as resistin and visfatin in the pathogenesis of insulin resistance is increasingly understood. In this study we aimed to evaluate the association between serum resistin levels and metabolic syndrome in bipolar disorder.
Method: 60 euthymic bipolar I disorder patients, of 29 under mood stabilizers (MS) (lithium, valproic acid, carbamazepin and lamotrigine) treatment and of 31, under atypical antipsychotics (AA) (risperidone, quetiapine and olanzapine) treatment for at least 3 months were enrolled. Control group consisted of 27 healthy members that has similar distribution of age, sex and BMI with the patients. Resistin, glucose, triglycerides and High Density Lipoprotein (HDL) were measured in all groups.
Results: Resistin levels were significantly high in bipolar patients than the controls. However, resistin levels were not significant difference between metabolic parameters patients and controls (p>0.05).
Conclusion: Serum resistin levels are high in bipolar patients, but not found association between with metabolic disturbances and treatment modality.

Key words: Bipolar disorder, resistin, metabolic disturbance

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How to Cite this Article

Pubmed Style

Yumru M, Gergerlioğlu HS, Savaş HA, Başaralı K, Kalenderoğlu A, Buyukbaş S. [Serum resistin levels and metabolic changes in bipolar disorder]. PBS. 2012; 2(2): 47-50. Turkish. doi:10.5455/jmood.20120516040842

Web Style

Yumru M, Gergerlioğlu HS, Savaş HA, Başaralı K, Kalenderoğlu A, Buyukbaş S. [Serum resistin levels and metabolic changes in bipolar disorder]. https://www.pbsciences.org/?mno=18624 [Access: June 22, 2026]. Turkish. doi:10.5455/jmood.20120516040842

AMA (American Medical Association) Style

Yumru M, Gergerlioğlu HS, Savaş HA, Başaralı K, Kalenderoğlu A, Buyukbaş S. [Serum resistin levels and metabolic changes in bipolar disorder]. PBS. 2012; 2(2): 47-50. Turkish. doi:10.5455/jmood.20120516040842

Vancouver/ICMJE Style

Yumru M, Gergerlioğlu HS, Savaş HA, Başaralı K, Kalenderoğlu A, Buyukbaş S. [Serum resistin levels and metabolic changes in bipolar disorder]. PBS. (2012), [cited June 22, 2026]; 2(2): 47-50. Turkish. doi:10.5455/jmood.20120516040842

Harvard Style

Yumru, M., Gergerlioğlu, . H. S., Savaş, . H. A., Başaralı, . K., Kalenderoğlu, . A. & Buyukbaş, . S. (2012) [Serum resistin levels and metabolic changes in bipolar disorder]. PBS, 2 (2), 47-50. Turkish. doi:10.5455/jmood.20120516040842

Turabian Style

Yumru, Mehmet, Hasan Serdar Gergerlioğlu, Haluk Asuman Savaş, Kemal Başaralı, Aysun Kalenderoğlu, and Sadık Buyukbaş. 2012. [Serum resistin levels and metabolic changes in bipolar disorder]. Psychiatry and Behavioral Sciences, 2 (2), 47-50. Turkish. doi:10.5455/jmood.20120516040842

Chicago Style

Yumru, Mehmet, Hasan Serdar Gergerlioğlu, Haluk Asuman Savaş, Kemal Başaralı, Aysun Kalenderoğlu, and Sadık Buyukbaş. "[Serum resistin levels and metabolic changes in bipolar disorder]." Psychiatry and Behavioral Sciences 2 (2012), 47-50. Turkish. doi:10.5455/jmood.20120516040842

MLA (The Modern Language Association) Style

Yumru, Mehmet, Hasan Serdar Gergerlioğlu, Haluk Asuman Savaş, Kemal Başaralı, Aysun Kalenderoğlu, and Sadık Buyukbaş. "[Serum resistin levels and metabolic changes in bipolar disorder]." Psychiatry and Behavioral Sciences 2.2 (2012), 47-50. Print.Turkish. doi:10.5455/jmood.20120516040842

APA (American Psychological Association) Style

Yumru, M., Gergerlioğlu, . H. S., Savaş, . H. A., Başaralı, . K., Kalenderoğlu, . A. & Buyukbaş, . S. (2012) [Serum resistin levels and metabolic changes in bipolar disorder]. Psychiatry and Behavioral Sciences, 2 (2), 47-50. Turkish. doi:10.5455/jmood.20120516040842

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