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Case Report 


Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease

Shazia Farheen Qureshi, Javed Ather Siddiqui, Yousef Bin Ahmed Shawosh.


Abstract
We report the case of a 20 year old unmarried female patient who has been diagnosed as schizophrenia with intellectual disability. Patient was on chlorpromazine since last three years subsequently develop hyperprolactinemia, later manifested into fibrocystic breast disease. Hyperprolactinemia, is known for decades as neglected side effect of antipsychotic medication. Prolactin is secreted in a pulsatile manner by the anterior pituitary gland. The main physiological function of prolactin is to cause breast enlargement and galactorrhea initially and later develop to fibrocystic breast disease. Routine investigation also revealed hypothyroidism. Prolactin is known as immunomodulator, and has been linked to benign or malignant tumor growth.

Key words: hyperprolactinemia, hypothyroidism, chlorpromazine, fibrocystic breast disease


 
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How to Cite this Article
Pubmed Style

Qureshi SF, Siddiqui JA, Shawosh YBA. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS. 2016; 6(4): 230-3. doi:10.5455/jmood.20161122123332

Web Style

Qureshi SF, Siddiqui JA, Shawosh YBA. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. https://www.pbsciences.org/?mno=240690 [Access: June 22, 2026]. doi:10.5455/jmood.20161122123332

AMA (American Medical Association) Style

Qureshi SF, Siddiqui JA, Shawosh YBA. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS. 2016; 6(4): 230-3. doi:10.5455/jmood.20161122123332


Vancouver/ICMJE Style

Qureshi SF, Siddiqui JA, Shawosh YBA. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS. (2016), [cited June 22, 2026]; 6(4): 230-3. doi:10.5455/jmood.20161122123332


Harvard Style

Qureshi, S. F., Siddiqui, . J. A. & Shawosh, . Y. B. A. (2016) Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. PBS, 6 (4), 230-3. doi:10.5455/jmood.20161122123332


Turabian Style

Qureshi, Shazia Farheen, Javed Ather Siddiqui, and Yousef Bin Ahmed Shawosh. 2016. Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. Psychiatry and Behavioral Sciences, 6 (4), 230-3. doi:10.5455/jmood.20161122123332


Chicago Style

Qureshi, Shazia Farheen, Javed Ather Siddiqui, and Yousef Bin Ahmed Shawosh. "Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease." Psychiatry and Behavioral Sciences 6 (2016), 230-3. doi:10.5455/jmood.20161122123332


MLA (The Modern Language Association) Style

Qureshi, Shazia Farheen, Javed Ather Siddiqui, and Yousef Bin Ahmed Shawosh. "Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease." Psychiatry and Behavioral Sciences 6.4 (2016), 230-3. Print. doi:10.5455/jmood.20161122123332


APA (American Psychological Association) Style

Qureshi, S. F., Siddiqui, . J. A. & Shawosh, . Y. B. A. (2016) Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease. Psychiatry and Behavioral Sciences, 6 (4), 230-3. doi:10.5455/jmood.20161122123332


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