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Case Report
Online Published: 30 Mar 2013
 


Agomelatine-induced elevation of liver enzymes

Gülçin Elboğa, Feridun Bülbül, Gökay Alpak, Ahmet Ünal, Haluk Savaş.


Abstract
Major depression is one of the most frequently seen psychiatric disorders. Classical antidepressant treatments might be insufficient in treating all symptoms of of depression. Therefore, antidepressant treatments which work through different mechanisms have been developed. One of these therapies is agomelatine. Agomelatine is a drug which is a synthetic analogue of melatonin hormone. Melatonin works by stimulating the activities of MT1 and MT2 receptors and inhibiting the activity of serotonin 5HT2C receptor. It is recommended to be cautious in patients taking agomelatine in terms of liver enzyme elevation. In this case report, agomelatine-induced elevation of liver enzymes and the treatment process will be presented.

Key words: agomelatine, elevated liver enzymes, major depression


 
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How to Cite this Article
Pubmed Style

Elboğa G, Bulbul F, Alpak G, Unal A, Savaş H. Agomelatine-induced elevation of liver enzymes. PBS. 2013; 3(1): 41-43. doi:10.5455/jmood.20121105064251

Web Style

Elboğa G, Bulbul F, Alpak G, Unal A, Savaş H. Agomelatine-induced elevation of liver enzymes. https://www.pbsciences.org/?mno=24495 [Access: June 27, 2026]. doi:10.5455/jmood.20121105064251

AMA (American Medical Association) Style

Elboğa G, Bulbul F, Alpak G, Unal A, Savaş H. Agomelatine-induced elevation of liver enzymes. PBS. 2013; 3(1): 41-43. doi:10.5455/jmood.20121105064251


Vancouver/ICMJE Style

Elboğa G, Bulbul F, Alpak G, Unal A, Savaş H. Agomelatine-induced elevation of liver enzymes. PBS. (2013), [cited June 27, 2026]; 3(1): 41-43. doi:10.5455/jmood.20121105064251


Harvard Style

Elboğa, G., Bulbul, . F., Alpak, . G., Unal, . A. & Savaş, . H. (2013) Agomelatine-induced elevation of liver enzymes. PBS, 3 (1), 41-43. doi:10.5455/jmood.20121105064251


Turabian Style

Elboğa, Gulcin, Feridun Bulbul, Gokay Alpak, Ahmet Unal, and Haluk Savaş. 2013. Agomelatine-induced elevation of liver enzymes. Psychiatry and Behavioral Sciences, 3 (1), 41-43. doi:10.5455/jmood.20121105064251


Chicago Style

Elboğa, Gulcin, Feridun Bulbul, Gokay Alpak, Ahmet Unal, and Haluk Savaş. "Agomelatine-induced elevation of liver enzymes." Psychiatry and Behavioral Sciences 3 (2013), 41-43. doi:10.5455/jmood.20121105064251


MLA (The Modern Language Association) Style

Elboğa, Gulcin, Feridun Bulbul, Gokay Alpak, Ahmet Unal, and Haluk Savaş. "Agomelatine-induced elevation of liver enzymes." Psychiatry and Behavioral Sciences 3.1 (2013), 41-43. Print. doi:10.5455/jmood.20121105064251


APA (American Psychological Association) Style

Elboğa, G., Bulbul, . F., Alpak, . G., Unal, . A. & Savaş, . H. (2013) Agomelatine-induced elevation of liver enzymes. Psychiatry and Behavioral Sciences, 3 (1), 41-43. doi:10.5455/jmood.20121105064251


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