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Online Published: 27 Sep 2013
 


Is there a clinical prodromal period for bipolar disorder?

Zerrin Binbay, Mustafa Solmaz, Selim Sağır, Derya Adalı.


Abstract
Bipolar disorder (BD) is a prevalent, chronic and heterogeneous psychiatric disorder. The diagnosis of BD, is often delayed and the development of the disorder is associated with suicidal behavior. Growing evidence from both preclinical and clinical literature, points to a clear need for improved early intervention in BD. Individuals who develop BD are often afflicted during their most vulnerable and formative years. A major factor contributing to the burden of disease is the substantial delay between the first experience of symptoms and the initiation of the treatment. Early stage or prodromal BD should be considered in clinical, neuropsychological and biological terms. Early interventions may prevent the development of the full disorder, or at least improve the outcome. The initial prodrome of BD is characterized by disregulation of mood and energy. Large scale longitudinal studies which have control groups are needed to validate these features and characterize their specificity and sensitivity.

Key words: bipolar disorder, prodromal period


 
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How to Cite this Article
Pubmed Style

Binbay Z, Solmaz M, Sağır S, Adalı D. [Is there a clinical prodromal period for bipolar disorder?]. PBS. 2013; 3(3): 114-8. Turkish. doi:10.5455/jmood20130621041331

Web Style

Binbay Z, Solmaz M, Sağır S, Adalı D. [Is there a clinical prodromal period for bipolar disorder?]. https://www.pbsciences.org/?mno=33583 [Access: June 23, 2026]. Turkish. doi:10.5455/jmood20130621041331

AMA (American Medical Association) Style

Binbay Z, Solmaz M, Sağır S, Adalı D. [Is there a clinical prodromal period for bipolar disorder?]. PBS. 2013; 3(3): 114-8. Turkish. doi:10.5455/jmood20130621041331


Vancouver/ICMJE Style

Binbay Z, Solmaz M, Sağır S, Adalı D. [Is there a clinical prodromal period for bipolar disorder?]. PBS. (2013), [cited June 23, 2026]; 3(3): 114-8. Turkish. doi:10.5455/jmood20130621041331


Harvard Style

Binbay, Z., Solmaz, . M., Sağır, . S. & Adalı, . D. (2013) [Is there a clinical prodromal period for bipolar disorder?]. PBS, 3 (3), 114-8. Turkish. doi:10.5455/jmood20130621041331


Turabian Style

Binbay, Zerrin, Mustafa Solmaz, Selim Sağır, and Derya Adalı. 2013. [Is there a clinical prodromal period for bipolar disorder?]. Psychiatry and Behavioral Sciences, 3 (3), 114-8. Turkish. doi:10.5455/jmood20130621041331


Chicago Style

Binbay, Zerrin, Mustafa Solmaz, Selim Sağır, and Derya Adalı. "[Is there a clinical prodromal period for bipolar disorder?]." Psychiatry and Behavioral Sciences 3 (2013), 114-8. Turkish. doi:10.5455/jmood20130621041331


MLA (The Modern Language Association) Style

Binbay, Zerrin, Mustafa Solmaz, Selim Sağır, and Derya Adalı. "[Is there a clinical prodromal period for bipolar disorder?]." Psychiatry and Behavioral Sciences 3.3 (2013), 114-8. Print.Turkish. doi:10.5455/jmood20130621041331


APA (American Psychological Association) Style

Binbay, Z., Solmaz, . M., Sağır, . S. & Adalı, . D. (2013) [Is there a clinical prodromal period for bipolar disorder?]. Psychiatry and Behavioral Sciences, 3 (3), 114-8. Turkish. doi:10.5455/jmood20130621041331


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