Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine

Nurdan Kasar; Cigdem Yektas; Ali Evren Tufan

doi:10.5455/PBS.20210419035444

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Original Research

PBS. 2021; 11(4): 243-248

doi: 10.5455/PBS.20210419035444

Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine

Nurdan Kasar, Cigdem Yektas, Ali Evren Tufan.

Abstract
Objective: The aim of our study is to evaluate treatment related adverse events in children with attention-deficit/ hyperactivity disorder (ADHD) using atomoxetine.
Material and Methods: One hundred one patients received atomoxetine treatment were included in this study. Evaluations were conducted with all participants and their parents using Turgay DSM-IV-Based Child and Adolescent Behavioral Disorders Screening and Rating Scale, Clinic Global Impression Scale and Atomoxetine Side Effect List.
Results: Decreased appetite, irritability, loss of weight, fatigue, abdominal pain, constipation, change in sleep patterns, dizziness were common adverse effects of atomoxetine in our study. Diarrhea, rash and skin picking were rare. Changes in sleep patterns were more frequent in patients with the inattentive subtype (χ2= 5.7, p=0.06, Cramers V= 0.25, Likelihood ratio). Patients using atomoxetine as the only treatment had constipation significantly more frequently than receiving multiple regimens (p=0.02).
Conclusions: Atomoxetine is generally safe and well tolerated. Further studies with a larger sample sized are required to investigate adverse effects of atomoxetine treatment

Key words: ADHD, atomoxetine, adverse events

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Pubmed Style

Kasar N, Yektas C, Tufan AE. Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine. PBS. 2021; 11(4): 243-248. doi:10.5455/PBS.20210419035444

Web Style

Kasar N, Yektas C, Tufan AE. Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine. https://www.pbsciences.org/?mno=74719 [Access: September 12, 2024]. doi:10.5455/PBS.20210419035444

AMA (American Medical Association) Style

Kasar N, Yektas C, Tufan AE. Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine. PBS. 2021; 11(4): 243-248. doi:10.5455/PBS.20210419035444

Vancouver/ICMJE Style

Kasar N, Yektas C, Tufan AE. Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine. PBS. (2021), [cited September 12, 2024]; 11(4): 243-248. doi:10.5455/PBS.20210419035444

Harvard Style

Kasar, N., Yektas, . C. & Tufan, . A. E. (2021) Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine. PBS, 11 (4), 243-248. doi:10.5455/PBS.20210419035444

Turabian Style

Kasar, Nurdan, Cigdem Yektas, and Ali Evren Tufan. 2021. Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine. Psychiatry and Behavioral Sciences, 11 (4), 243-248. doi:10.5455/PBS.20210419035444

Chicago Style

Kasar, Nurdan, Cigdem Yektas, and Ali Evren Tufan. "Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine." Psychiatry and Behavioral Sciences 11 (2021), 243-248. doi:10.5455/PBS.20210419035444

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Kasar, N., Yektas, . C. & Tufan, . A. E. (2021) Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine. Psychiatry and Behavioral Sciences, 11 (4), 243-248. doi:10.5455/PBS.20210419035444

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